Quick Answer: What Are the Best Supplements to Take in Your 60s?

A fast summary before we get into the science.

• Marine collagen peptides support skin elasticity, hydration, and hair-shaft strength as your body's natural collagen production declines with age.
• Biotin, vitamin D, iron, and zinc address the nutrient gaps most commonly linked to thinning hair and slower regrowth in people over 60.
• DHT-blocking botanicals like saw palmetto, nettle root, and pumpkin seed extract can help counter the hormone-driven hair miniaturization that accelerates after menopause and with age-related testosterone shifts.
• MDhair's Restore and Regrowth Supplements combine these categories into dermatologist-formulated capsules designed specifically for age-related hair thinning, with marine collagen and antioxidants that double as skin-support nutrients.
• Women taking GLP-1 medications (semaglutide, tirzepatide) are especially prone to nutrient-gap hair shedding and collagen-depleted, sagging skin — making MDhair Restore Supplements and marine collagen a particularly good fit for this growing group.
• Supplements work best as one part of a routine that also includes topical actives, sun protection, and — when appropriate — medical treatments like minoxidil.

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Why Do Hair and Skin Change So Much in Your 60s?

Understanding the biology behind this decade's changes makes it easier to choose supplements that actually address the cause.

By your 60s, several biological processes are converging at once. Estrogen and testosterone levels have shifted significantly, collagen synthesis has slowed by an estimated 1–1.5% per year since your mid-20s, and hair follicles have spent decades accumulating sensitivity to dihydrotestosterone (DHT), the hormone responsible for androgenetic alopecia in both men and women [1]. The result is a predictable pattern: thinner hair strands, a widening part line, drier and less elastic skin, and slower wound healing.

A randomized controlled study in menopausal women found that six months of combined collagen, calcium, and vitamin D3 supplementation improved skin hydration by 23% and skin elasticity by over 8%, while also measurably slowing hair shedding compared to placebo [2]. That single study captures why hair and skin supplements are so often discussed together at this life stage — they share overlapping nutritional dependencies, particularly around collagen production, oxidative stress, and micronutrient status.

Nutrient deficiencies also become more common with age due to changes in absorption, medication interactions, and dietary shifts. Vitamin D deficiency, in particular, has been implicated in hair-cycle disruption and is one of the most common deficiencies identified in adults over 60 [3]. This is why a targeted supplement strategy — rather than a single "hair vitamin" — tends to produce better results than any one ingredient alone.

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Which Nutrients Matter Most for Hair Health After 60?

Not all hair supplements are created equal — here's what the evidence actually supports.

Biotin (Vitamin B7)

Biotin supports keratin infrastructure, the structural protein that makes up the hair shaft. While biotin deficiency is relatively rare, supplementation shows the most benefit in people who are deficient, and evidence for biotin in non-deficient individuals is more limited [4]. Still, it remains a foundational ingredient in nearly every dermatologist-formulated hair supplement because of its low risk profile and role in follicle strength.

Vitamin D3

Low vitamin D has been linked to alopecia areata and other hair-cycle disruptions, and deficiency becomes markedly more common with age due to reduced sun exposure and skin synthesis efficiency [3]. Correcting a deficiency can meaningfully support regrowth in people who are low.

Iron and Zinc

Iron carries oxygen to the hair follicle and is essential for the anagen (growth) phase of the hair cycle; deficiency is a well-documented, correctable cause of diffuse thinning [5]. Zinc and selenium support follicle repair and are frequently depleted in older adults with lower dietary variety.

Marine Collagen Peptides

Collagen supplies glycine and proline, the amino acids required to build keratin. Beyond hair, marine-sourced collagen has demonstrated measurable improvements in skin hydration and elasticity in clinical trials, with the added benefit of supporting a healthier, better-hydrated scalp environment — a factor that matters more than people realize for follicle health [2].

DHT-Blocking Botanicals

Saw palmetto inhibits the same 5-alpha-reductase enzyme pathway targeted by prescription finasteride, making it one of the few over-the-counter botanicals with a genuine mechanistic rationale for slowing androgenetic hair thinning [6]. Nettle root and pumpkin seed extract are often paired with saw palmetto for a broader DHT-modulating effect.

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How Do MDhair Supplements Support Hair (and Skin) in Your 60s?

This is where the science translates into a practical, dermatologist-formulated product strategy.

MDhair, a sister brand under the same dermatology-led platform as Nuvane, formulates two supplement lines specifically to address age-related and hormone-driven hair thinning — the exact pattern most common in your 60s.

MDhair Restore Supplements are built around a broad nutrient-repletion formula: biotin, vitamins C, E, B6, B12, and B5, iron, iodine, magnesium, zinc, selenium, and chromium. This addresses the nutrient-gap side of hair thinning directly, providing the raw materials the follicle needs during its growth phase while also supporting the antioxidant defenses that protect skin from oxidative aging.

MDhair Regrowth Supplements take a more targeted, hormone-focused approach. The formula pairs saw palmetto, nettle leaf extract, and Reishi and Maitake mushroom extracts to blunt the effects of DHT on the follicle, alongside vitamins E, D, B6, folic acid, biotin, zinc, selenium, and copper for follicle-level repair. Some formulations also include ashwagandha root extract, an adaptogen that helps regulate cortisol — relevant because chronic stress is an underappreciated accelerant of hair shedding at any age.

For skin, the shared benefit comes largely through marine collagen, offered as part of MDhair's more comprehensive kits. Marine collagen's high glycine and proline content supports keratin production for hair while simultaneously improving skin elasticity and hydration — the same mechanism Nuvane's own clinical data highlights when we talk about skin longevity. This is a good example of why we think about hair and skin nutrition together rather than treating them as separate categories: a well-hydrated scalp, supported by the same collagen and antioxidant pathways that firm and hydrate facial skin, is a healthier environment for follicles to do their job.

If you're also using topical retinol or bakuchiol as part of a Nuvane routine, internal collagen support from a supplement like MDhair's marine collagen complements that work rather than duplicating it — topicals stimulate collagen synthesis at the dermal level, while oral collagen peptides supply the amino acid building blocks the skin needs to use that stimulation effectively. Nuvane's own Oral Marine Collagen Supplement, paired with vitamin C and hyaluronic acid, follows the same evidence-based logic, and our SenoP3™ triple-peptide complex (Palmitoyl Tripeptide-38, Copper Tripeptide-1/GHK-Cu, and Acetyl Hexapeptide-8) works topically to stimulate the same collagen and elastin pathways from the outside in.

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Are MDhair Restore Supplements and Marine Collagen Especially Good for Women on GLP-1s?

A growing number of women in their 60s are combining GLP-1 medications with anti-aging routines — here's why this nutrient pairing matters more for this group.

Yes — women on GLP-1 receptor agonists (semaglutide, tirzepatide, and related medications) face a distinct version of the hair and skin changes discussed above, and it tends to hit harder and faster. Appetite suppression is the mechanism behind GLP-1 weight loss, but it also means significantly reduced food intake, which raises the risk of falling short on protein, iron, zinc, biotin, and vitamin D — the exact nutrients hair follicles depend on for the anagen growth phase [9]. Dermatologists have also observed that the rapid pace of GLP-1-driven weight loss can push a larger percentage of follicles into telogen effluvium, a stress-triggered shedding phase, and — unlike a single stressful event — the shedding can persist for as long as the weight loss continues [10].

Skin faces a parallel challenge. Collagen depends on adequate protein and steady blood supply to the dermis, both of which are affected by rapid fat loss. The resulting loss of facial and body volume, crepiness, and reduced elasticity — often called "Ozempic skin" or "Ozempic face" — reflects a mismatch between how quickly the fat compartment shrinks and how slowly collagen and skin structure can adapt [11]. Dermatology guidance on this topic consistently points to the same fix: replace what rapid weight loss is depleting, specifically collagen and the vitamins that support its synthesis [12].

This is precisely the gap MDhair Restore Supplements are built to close. The formula's broad-spectrum approach — biotin, vitamins C, E, B6, B12, and B5, iron, iodine, magnesium, zinc, selenium, and chromium — directly replaces the micronutrients most likely to run low on a reduced-calorie, GLP-1-suppressed appetite, rather than requiring a woman to correct a dozen individual deficiencies through diet alone. Because vitamin C and zinc are also required cofactors for collagen synthesis, Restore Supplements support skin resilience at the same time they support the hair follicle.

Marine collagen rounds out the strategy. Since collagen is a protein, and GLP-1 users are frequently protein-deficient by volume even when calorie intake is adequate, supplementing with marine collagen peptides provides a concentrated, easily absorbed source of the glycine and proline needed to rebuild dermal structure and keratin alike [13]. For women managing visible facial changes on a GLP-1, pairing an oral marine collagen supplement with a topical routine built around retinol, bakuchiol, or SenoP3™ addresses the skin-support side of GLP-1 use from both the inside and the outside — the same layered logic dermatologists recommend for slowing "Ozempic face" while continuing treatment [11].

If you're on a GLP-1 and noticing more hair in the shower drain or looser-feeling skin, this combination is worth raising with your prescribing physician or dermatologist, both to rule out other causes and to confirm supplementation won't interact with your current medications.

The right choice depends on what's actually driving your hair changes.

• If bloodwork shows a deficiency (common in vitamin D, iron, or B12), a nutrient-repletion formula like MDhair Restore Supplements addresses the root cause directly.
• If your hair loss follows a hormonal pattern — thinning at the crown, widening part, or a receding hairline — a DHT-blocking formula like MDhair Regrowth Supplements targets the mechanism more precisely.
• If you want a comprehensive approach, combining both nutrient support and DHT-blocking botanicals, alongside a topical treatment, tends to outperform any single intervention. This mirrors how we approach skin longevity at Nuvane: layered support beats a single "miracle ingredient."
• A simple blood panel (vitamin D, ferritin/iron, B12, thyroid function) before starting supplementation helps target your regimen instead of guessing.

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Key Takeaways

• Hair and skin changes in your 60s share overlapping causes: declining collagen synthesis, accumulated DHT sensitivity, and more common nutrient deficiencies.
• Biotin, vitamin D, iron, and zinc correct the most common nutrient gaps linked to thinning hair.
• Saw palmetto, nettle root, and pumpkin seed extract offer a mechanistic, DHT-blocking approach similar in pathway to prescription hair-loss treatments.
• Marine collagen supports both hair-shaft strength and skin elasticity/hydration, making it one of the few ingredients that genuinely serves double duty.
• MDhair Restore and Regrowth Supplements were formulated by dermatologists to target these exact mechanisms for age-related thinning.
• Supplements are most effective as part of a broader routine — pairing internal nutrition with topical actives like retinol, bakuchiol, or SenoP3™ addresses skin and hair aging from both directions.

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Frequently Asked Questions

Is it safe to take hair supplements in your 60s?

Most hair and nutrient-support supplements, including biotin, marine collagen, and saw palmetto, have a favorable safety profile for adults over 60. That said, biotin can interfere with certain thyroid and cardiac blood tests, so let your physician know if you're supplementing before lab work [7].

How long does it take to see results from hair supplements?

Because the hair growth cycle spans several months, most clinical studies measure results at 3–6 months of consistent use. Expect gradual changes in shedding and density rather than immediate results.

Can supplements alone reverse age-related hair thinning?

Supplements address nutritional and, in the case of DHT-blockers, hormonal contributors to thinning, but they work best combined with topical treatments and, when appropriate, medical options like minoxidil for more advanced thinning.

Do I need different supplements for hair versus skin in my 60s?

Not entirely — collagen, vitamin C, zinc, and antioxidants support both. However, DHT-blocking botanicals are specific to hair, while ingredients like SenoP3™ peptides are formulated specifically for topical skin application.

Is marine collagen better than other collagen sources for hair and skin?

Marine collagen has smaller peptide particle sizes than bovine or porcine collagen in some formulations, which may support better bioavailability, though more head-to-head clinical research is still needed [8].

Should men and women in their 60s take the same supplements?

The core nutrient needs overlap significantly, but hormonal drivers of hair thinning differ. Both men and women can benefit from DHT-blocking botanicals, since androgenetic alopecia affects both sexes, though the pattern of thinning differs.

Can I take MDhair supplements alongside my Nuvane skincare routine?

Yes. MDhair's internal supplements and Nuvane's topical actives target complementary pathways — oral nutrients build the raw materials for collagen and keratin, while topical retinol, bakuchiol, and SenoP3™ stimulate the skin directly. There's no conflict between the two.

Do I need a blood test before starting supplements?

It's not required, but checking vitamin D, ferritin, and B12 levels can help you target your supplement choice rather than taking a broad-spectrum formula unnecessarily.

Can I take MDhair supplements while on Ozempic, Wegovy, or another GLP-1?

Many women use MDhair Restore Supplements and marine collagen alongside GLP-1 therapy to offset the nutrient gaps and collagen loss associated with rapid weight loss, but always confirm with your prescribing physician first, since individual medication interactions and health histories vary.

References

• Ceruti JM, et al. "Androgens and androgenetic alopecia: exploring the pathogenic mechanisms." Journal of Steroid Biochemistry and Molecular Biology, 2018.
• Randomized Controlled Study. "Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women." 2026.
• Saini K, et al. "Role of Vitamin D in hair loss: a short review." Journal of Cosmetic Dermatology, 2021.
• Patel MN, et al. "A review of the use of biotin for hair loss." Skin Appendage Disorders, 2025.
• Trost LB, et al. "The diagnosis and treatment of iron deficiency and its potential relationship to hair loss." Journal of the American Academy of Dermatology, 2006.
• Rossi A, et al. "Comparison of finasteride vs. Serenoa repens in male androgenetic alopecia: a two-year study." International Journal of Immunopathology and Pharmacology, 2012.
• Li D, et al. "Association of biotin ingestion with performance of hormone and non-hormone assays in healthy adults." JAMA, 2017.
• Vleminckx S, et al. "Collagen peptides and skin health: mechanisms and bioavailability considerations." Nutrients, 2024.
• Holman J, et al. "Nutritional considerations and hair shedding in patients on GLP-1 receptor agonist therapy." American Academy of Dermatology clinical commentary, 2025.
• Brown T, et al. "GLP-1 receptor agonists and telogen effluvium: metabolic and nutritional contributors." Journal of Clinical Endocrinology & Metabolism, 2022.
• American Academy of Dermatology. "How can GLP-1 drugs affect my skin, hair, and nails?" Patient education guidance, 2026.
• Women's Health Network. "Nutrient support strategies during GLP-1 weight loss therapy." Clinical nutrition guidance, 2026.
• Garshick M. "Protein and collagen intake during rapid weight loss: implications for skin and hair." Dermatology practice commentary, 2025.

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• MDhair Restore Supplements — biotin, vitamin C, E, B6, B12, B5, iron, iodine, magnesium, zinc, selenium, and chromium for nutrient-gap hair thinning.
• MDhair Regrowth Supplements — saw palmetto, nettle leaf, and Reishi/Maitake mushroom extracts to target DHT-driven hair loss.
• MDhair Marine Collagen — hydrolyzed marine collagen with hyaluronic acid and vitamin C for hair, skin, and nail elasticity and hydration.

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