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How camellia extract fights aging cells naturally?

Yoram Harth, MD
By Yoram Harth, MD | Oct 19, 2025


A healthy scalp is the foundation of healthy hair. However, scalp fibroblasts and follicular stem cells also undergo senescence, especially under oxidative stress, hormonal shifts, and UV exposure (5).

Camellia extract helps counter these effects by:

  • Neutralizing free radicals that damage follicles
  • Reducing scalp inflammation linked to hair loss
  • Supporting microcirculation and oxygenation around follicles
  • Encouraging hair anchoring and root strength

Together, these actions help extend the anagen (growth) phase of hair and maintain a denser, healthier scalp ecosystem.


How MDhair Uses Camellia Extract in Its Science-Backed Haircare

MDhair has integrated Camellia-derived actives in its most advanced restorative formulas—each designed to support the scalp’s cellular health and rebuild hair from root to tip.

Below are the MDhair products powered by Camellia extract, with a detailed look at their scientifically supported benefits.


1. MDhair Regrowth Serum — Camellia sinensis (Green Tea) Extract

A clinically formulated serum targeting scalp aging and follicle resilience, enriched with Camellia sinensis extract—one of nature’s most powerful sources of catechins, polyphenols, and antioxidants.

Key Benefits:

  • Stimulates hair regrowth by protecting dermal papilla cells from oxidative stress and DHT-induced miniaturization (6).
  • Improves scalp microcirculation, promoting better nutrient and oxygen delivery to follicles.
  • Reduces inflammation through EGCG (epigallocatechin gallate), calming redness and soothing irritation.
  • Protects against environmental aggressors, shielding the scalp from pollution and UV-related aging.
  • Enhances cellular metabolism, supporting faster follicular turnover and thicker strands.
  • Balances sebum production, helping maintain a clean, non-greasy scalp environment.

Mechanism of Action:
Camellia sinensis acts through antioxidant signaling and modulation of NF-κB and TGF-β pathways—two critical cascades involved in follicular inflammation and senescence (7).


2. MDhair Peptide Bond Repair Oil — Camellia japonica Leaf Extract

An advanced oil treatment featuring Camellia japonica Leaf Extract, formulated to repair damage, strengthen hair bonds, and restore lipid balance.

Key Benefits:

  • Deep hydration and shine: Camellia oil’s oleic acid mimics natural sebum, delivering weightless moisture.
  • Repairs damaged bonds: Peptide complexes and Camellia extract strengthen internal hair structure.
  • Protects from heat and UV: Polyphenols form a natural shield against oxidative and thermal stress.
  • Restores elasticity and smoothness: Improves the flexibility of aging or chemically treated hair.
  • Reduces frizz and breakage: Lipid replenishment smooths the cuticle, preventing further damage.
  • Supports scalp health: Anti-inflammatory phytochemicals soothe the scalp, promoting a healthy base for regrowth.

Mechanism of Action:
Camellia japonica extract is rich in saponins and flavonoids that enhance keratin cross-linking and lipid organization in the hair shaft, leading to visible improvements in texture and resilience (8).


3. Synergistic Benefits of Using Both Products Together

When used as a system, MDhair Regrowth Serum + Peptide Bond Repair Oil offers a full-spectrum anti-aging strategy for hair and scalp:

  • Regrowth Serum targets cellular renewal at the follicle level.
  • Repair Oil restores structural integrity from the outside in.

Combined, they:

  • Reactivate dormant follicles
  • Reinforce hair fiber strength
  • Improve scalp oxygenation and barrier resilience
  • Deliver antioxidant protection for long-term vibrancy

This inside-out synergy aligns with MDhair’s philosophy: restore balance, renew cellular vitality, and protect the natural beauty of hair through science-backed botanicals.


The Broader Picture: Camellia in “Senescence-Aware” Beauty

The discovery of Camellia’s CXCL9-boosting properties signals a shift toward senescence-aware formulations—products designed not just to conceal aging but to support the body’s innate renewal mechanisms.

In skincare and haircare, this means:

  • Activating immune cleansing of damaged cells
  • Rebooting regenerative signaling in fibroblasts and follicles
  • Reducing chronic inflammation to slow visible aging
  • Enhancing biological resilience for long-lasting radiance

Camellia stands at the center of this evolution—a bridge between traditional botanical care and modern cellular science.


Safety, Sustainability, and Purity

Both Camellia sinensis and Camellia japonica are non-irritating, non-sensitizing botanicals. Their gentle lipid profile makes them suitable for all hair types, including color-treated, dry, or mature hair.

MDhair sources its Camellia ingredients through eco-conscious extraction and traceable supply chains, ensuring minimal environmental impact. Many components are upcycled from the tea and Camellia oil industries, turning natural byproducts into high-performance skincare-grade actives.


What Results Can You Expect From Regular Use?

With consistent use, users typically notice:

  • Within 4–6 weeks: Calmer scalp, improved shine, reduced breakage
  • Within 8–12 weeks: Fuller appearance, stronger strands, less shedding
  • Over time: Visibly thicker, more resilient hair and a balanced, healthy scalp

These improvements reflect not just cosmetic benefits, but real biological rejuvenation at the cellular level.


References

  1. van Deursen JM. Nature. 2014;509:439–446.
  2. Shiseido R&D Report, 2024. “Fermented Camellia Seed Extract Promotes CXCL9 Expression.”
  3. Jung UJ, et al. J Med Food. 2017;20(5):441–448.
  4. Liao YC, et al. Immunity. 2019;50(2):561–575.
  5. Birch-Machin MA, Bowman A. Br J Dermatol. 2016;175(S2):13–17.
  6. Kwon OS, et al. Phytother Res. 2007;21(10):958–962.
  7. Choi SY, et al. J Cosmet Dermatol. 2019;18(5):1400–1411.
  8. Kim YH, et al. Cosmet Sci Tech. 2020;73(2):205–212.
  9. Nuvane Project Documentation, MDhair Ingredient Research 2024.
  10. Park S, et al. Arch Dermatol Res. 2022;314(8):677–690.

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