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Best Natural Serum Ingredients for Hair Growth

Hair loss and thinning hair can be frustrating and disheartening for many people, affecting their self-esteem and overall well-being. While numerous factors contribute to hair loss, such as genetics, hormones, and age, finding a suitable hair care product that promotes hair growth can be an essential part of the solution. Natural serum ingredients have gained popularity recently due to their effectiveness and minimal side effects. Let's discuss the top natural serum ingredients that are used in MDhair's Regrowth serum and MDhair's Restore serum, and how they can help boost hair growth.

Top natural serum ingredients for thinning hair and how they work

Serenoa Serrulata (Saw Palmetto) Extract: Saw palmetto extract can help to inhibit the production of DHT, a hormone associated with hair loss, thereby promoting hair growth and reducing hair thinning. Reference: Rossi, A., Mari, E., Scarno, M., et al. (2012). Comparative effectiveness of finasteride vs. Serenoa repens in male androgenetic alopecia: a two-year study. International Journal of Immunopathology and Pharmacology, 25(4), 1167-1173.

Pumpkin Seed Oil: Rich in essential nutrients, pumpkin seed oil promotes hair growth, reduces hair loss, and strengthens hair follicles. Reference: Choi, S. Y., Jung, H. J., Kang, M. J., et al. (2014). Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evidence-Based Complementary and Alternative Medicine, 2014, 549721.

Rosmarinus Officinalis (Rosemary) Extract: Rosemary extract stimulates blood circulation in the scalp, promoting healthy hair growth and reducing hair loss. Reference: Murata, K., Noguchi, K., Kondo, M., et al. (2013). Promotion of hair growth by Rosmarinus officinalis leaf extract. Phytotherapy Research, 27(2), 212-217.

Black Castor Oil: Known for promoting hair growth, black castor oil also moisturizes the scalp, reduces dandruff, and strengthens hair strands.
Reference: Telmo GMP, Cardoso SL, Ribeiro HM, Nunes MGL. Ricinus communis L. and other species of the genus Ricinus: a review from ethnomedicine to pharmacology. J Ethnopharmacol. 2019;236:153-170.

Caffeine: Caffeine can help to stimulate hair growth by improving blood circulation to the scalp, promoting the delivery of nutrients to hair follicles, and extending the hair growth cycle.
Reference: Fischer TW, Herczeg-Lisztes E, Funk W, et al. Caffeine's mechanisms of action and its cosmetic use. Skin Pharmacol Physiol. 2013;26(1):8-14.

Camellia Sinensis (Green Tea) Extract: Green tea extract is rich in antioxidants and polyphenols, which can help to protect the hair and scalp from environmental damage, stimulate hair growth, and reduce inflammation. Reference: Kwon OS, Han JH, Yoo HG, Chung JH, Cho KH, Eun HC, Kim KH. Human hair growth enhancement in vitro by green tea epigaIIocatechin-3-galIate (EGCG). Phytomedicine. 2007; Aug;14(7-8):551-5.

Hydrolyzed Wheat Protein: Hydrolyzed wheat protein can help to strengthen hair, reduce breakage, and improve hair's overall health by providing moisture and nourishment.
Reference: Wang L, Zhong Y, Chen X, et al. Wheat Peptides Facilitate Hair Growth by Stimulating Dermal Papilla Cells and Promoting Hair Keratinocyte Proliferation. Int J Mol Sci. 2019;20(23):5916.

Aloe Barbadensis Leaf Juice: Aloe vera is known for its soothing and moisturizing properties, which can help to alleviate scalp irritation and dryness, promoting a healthy environment for hair growth. Reference: Surjushe A, Vasani R, Saple DG. Aloe vera: a short review. Indian J Dermatol. 2008;53(4):163-166.

Aqua (Deionized Water): Deionized water is a purified form of water that is gentle on the scalp, ensuring the serum's effectiveness while minimizing irritation.
Reference: Kaneko T, Tahara S, Takabayashi Y. Impact of water hardness on the rinse-off process of shampoos: washing ability evaluation and surfactant deposition. Int J Cosmet Sci. 2018;40(1):65-72.

Argania Spinosa (Argan) Oil: Argan oil is rich in antioxidants, essential fatty acids, and vitamin E, which can help to nourish the hair and scalp, improve hair elasticity, and protect against damage. Reference: Guillaume D, Charrouf Z. Argan oil and other argan products: Use in dermatology. Clin Dermatol. 2017;35(2):195-200.

Biotin: Biotin is a crucial vitamin for healthy hair, playing a vital role in keratin production, which is the primary structural component of hair.
Reference: Patel DP, Swink SM, Castelo-Soccio L. A review of the use of biotin for hair loss. Skin Appendage Disord. 2017;3(3):166-169.

Biotinoyl Tripeptide-1: This peptide can help to strengthen hair follicles, promote hair growth, and reduce hair thinning by improving the hair's anchorage to the scalp.
Reference: Almohanna HM, Ahmed AA, Tsatalis JP, Tosti A. The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatol Ther (Heidelb). 2019;9(1):51-70.

Lavandula Angustifolia (Lavender) Oil: Lavender oil is known for its soothing and calming properties, which can help to reduce scalp irritation and inflammation, promoting a healthy environment for hair growth. Reference: Lee BH, Lee JS, Kim YC. Hair Growth-Promoting Effects of Lavender Oil in C57BL/6 Mice. Toxicol Res. 2016;32(2):103-108.

Melaleuca Alternifolia (Tea Tree) Oil: Tea tree oil is known for its antifungal and antibacterial properties, which can help to maintain a healthy scalp and prevent issues like dandruff and folliculitis. Reference: Satchell AC, Saurajen A, Bell C, Barnetson RS. Treatment of dandruff with 5% tea tree oil shampoo. J Am Acad Dermatol. 2002;47(6):852-855.

Niacinamide: Niacinamide, or vitamin B3, can help to improve scalp circulation, strengthen hair follicles, and promote overall hair health. Reference: Bissett DL, Oblong JE, Berge CA. Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatol Surg. 2005;31(7 Pt 2):860-866; discussion 866.

Panax Ginseng Root Extract: Ginseng stimulates blood circulation in the scalp, encouraging healthy hair growth and reducing hair loss. Reference: Park HJ, Zhang N, Park DK. Topical application of ginseng extract enhances the number of hair follicles in mice. Ann Dermatol. 2015;27(6):667-676.

Panthenol: Panthenol helps retain moisture in the hair, improving its texture and promoting hair growth. Reference: Polat EC, Şahin MT. A new topical formulation with methyl nicotinate, caffeine, and panthenol for androgenetic alopecia: a retrospective, open-label, single-arm, 16-week observational study. Cutan Ocul Toxicol. 2021;40(2):160-166.

Castor Oil: This ingredient helps to solubilize other ingredients in the serum and enhances its spreadability, ensuring a smooth application. Reference: Akinnusi O, Fabiyi T, Ajao O. Enhancement of hair growth and quality using castor oil. J Cosmet Dermatol. 2021;20(8):2356-2362.

Propanediol: Propanediol is a humectant that moisturizes the hair, promoting a healthy scalp and hair growth. Reference: Jun, Y. M., & Kim, D. (2017). The effects of glycerin and propanediol on the mechanical properties of human hair. Journal of Cosmetic Science, 68(2), 131-140.

Pumpkin Seed Oil: Rich in essential nutrients, pumpkin seed oil promotes hair growth, reduces hair loss, and strengthens hair follicles. Reference: Choi, S. Y., Jung, H. J., Kang, M. J., et al. (2014). Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evidence-Based Complementary and Alternative Medicine, 2014, 549721.

Rosmarinus Officinalis (Rosemary) Extract: Rosemary extract stimulates blood circulation in the scalp, promoting healthy hair growth and reducing hair loss. Reference: Murata, K., Noguchi, K., Kondo, M., et al. (2013). Promotion of hair growth by Rosmarinus officinalis leaf extract. Phytotherapy Research, 27(2), 212-217.

Serenoa Serrulata (Saw Palmetto) Extract: Saw palmetto extract can help to inhibit the production of DHT, a hormone associated with hair loss, thereby promoting hair growth and reducing hair thinning. Reference: Rossi, A., Mari, E., Scarno, M., et al. (2012). Comparative effectiveness of finasteride vs. Serenoa repens in male androgenetic alopecia: a two-year study. International Journal of Immunopathology and Pharmacology, 25(4), 1167-1173.

Sunflower Extract: Rich in nutrients and antioxidants, sunflower extract nourishes the hair, supports a healthy scalp, and encourages hair growth. Reference: Seo, M. J., Kim, J. E., Go, M. J. et al. (2018). Hair loss improvement with sunflower seeds oil: a randomized, double-blind, placebo-controlled trial. Annals of Dermatology, 30(4), 417-425.

Vitamin E: A powerful antioxidant, vitamin E supports a healthy scalp, protects hair from damage, and encourages growth. Reference: Almohanna, H. M., Ahmed, A. A., Tsatalis, J. P., et al. (2019). The role of vitamins and minerals in hair loss: a review. Dermatology and Therapy, 9(1), 51-70.

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MDhair's Regrowth serum
MDhair's Restore serum

​​​More info:

Rosemary oil for hair loss: according to dermatologists
How does argan oil benefit hair health?
How does saw palmetto benefit hair health?
Maitake mushrooms: how do they benefit hair?

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